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EDITORIAL BOARD MEMBER - Dr. Munir Al-Zeer

Dr. Munir Al-Zeer

Max Planck Institute for Infection Biology
Germany

BIOGRAPHY:

Dr. Munir Al-Zeer is a Scientist in the Department of Molecular Biology at Max Planck Institute for Infection Biology. He obtained a B.Sc. in Biological Sciences at the University of Jordan, where he also did his M.Sc. in Microbiology and Immunology. In 2009, he did his Ph.D. (DAAD Ph.D. Award) under Dr. Thomas Meyer supervision at Humboldt University of Berlin, studying Host-Pathogen Interactions where he revealed the role of interferon γ-inducible GTPases in immunity against Chlamydia. In particular, he discovered that the immunity-related GTPases (IRGs) are required for protection against Chlamydia in vitro. These findings provide novel insight into the differences between C. muridarum and C. trachomatis infections, autophagy and innate immunity. His post-doctoral studies were performed with Dr. Thomas Meyer at the Department of Molecular Biology at Max Planck Institute for Infection Biology, where he investigated the anti-chlamydial activity of interferon γ-inducible GTPases termed Guanylate Binding Proteins (GBPs) in human macrophages. Dr. Al-Zeer's research interests are focused on host-pathogen interactions, at the molecular level. By combining cell biology with microbiology, he has been making several fundamental discoveries in this field including the discovery of microtubule-dependent association of LC3 with the Chlamydia-containing vacuole, which is distinct from autophagy. In addition, his work uncovered new interactions between C. trachomatis and the host cell stable microtubule. Moreover, Dr. Al-Zeer initiated a new model for the study of host-pathogen interactions, using a primary cell model, instead of the widely used cancerous cell lines. This new model served to reveal the mechanism by which intracellular pathogen survives the innate immune response, iNOS, of the host.

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