Research Article
Serodynamic and Clinical Significance of Anti-Rubella Antibodies in Young Female Domiciled in Benin City and its Environs
Ibadin OK, Osemwemkha AP and Ibadin NO
Correspondence Address :
Ibadin OK
Human Reproduction Research Programme/In-Vitro Fertilization Centre
Department of Obstetrics and Gynaecology
University of Benin Teaching Hospital
Benin City
Nigeria
Email: kenbadin1@yahoo.com
Received on: April 4, 2016, Accepted on: May 11, 2016, Published on: May 20, 2016
Citation: Ibadin OK, Osemwemkha AP, Ibadin NO (2016). Serodynamic and Clinical Significance of Anti-Rubella Antibodies in Young Female
Domiciled in Benin City and its Environs
Copyright: 2016 Ibadin OK, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract
Rubella is a disease of childhood and individual infected by this organism experience mild prodromal symptoms. The prevention of congenital rubella syndrome is the ultimate goal of any nation through wide vaccination programs for these young females. In this present study blood samples were collected for serum extraction from 199 test subjects with age range from 5-29 years. The collected sera were screened for rubella antibodies (IgG) using the Enzyme linked Immuno Sorbent Assay techniques (ELIZA). This study detected (80.4%) seroevidence rate for the rubella IgG antibodies with the ELIZA method. Also detected and observed was the high seroevidence rate of young females from the urban areas with (82.5%) who were found to be more prevalent than other young females from the rural areas with (17.5%). The study also detected high susceptibility of rubella infection among young females in the age group 20-24 with (7.75%). The objective was to assess the level of immunity of young females in an attempt to evaluate the need of mass immunization. We recommended vaccination of young females of reproductive age and also carryout immunization on the seronegative young female that are also susceptible.
Keywords: Anti rubella antibodies, Clinical significance, Young females