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Journal of Blood Disorders Symptoms and Treatments

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Case Report

Therapeutic Management in a Patient with Homozygous Sickle Cell Disease and Prior Pulmonary Embolism during the Pregnancy - A Case Report

Notter J, Amstad G, Drexler B, Loukidis K

Correspondence Address :

K. Loukidis
Department of Medicin
Kantonsspital Baselland -Bruderholz
Email: loukidiskonstantinos@gmail.com

Received on: October 16, 2017, Accepted on: October 24, 2017, Published on: October 31, 2017

Citation: Notter G, Amstad G, Drexler B, Loukidis K (2017). Therapeutic Management in a Patient with Homozygous Sickle Cell Disease and Prior Pulmonary Embolism during the Pregnancy - A Case Report

Copyright: 2017 K. Loukidis et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

  • Abstract

Abstract
Introduction: Pregnancy in patients with sickle cell disease is associated with high risk of maternal and fetal morbidity and mortality. SCD patients have a higher risk of deep vein thrombosis and pulmonary embolism, especially during pregnancy and post-partum. There are still unresolved issues regarding the optimal management of pregnancy in SCD. The objective of our paper is to describe one possible approach to patients with SCD, pregnancy and prior PE using a case description.
Case Description: We describe the case and clinical management of a successful pregnancy of a 30-year-old patient with homozygous SCD and status after two miscarriages and PE.
Conclusion: A successful pregnancy in a high-risk patient with SCD and prior PE was possible with the aid of LMWH and Aspirin. Interdisciplinary collaboration is recommended to achieve a successful outcome. Further prospective studies are needed to optimize management of pregnancy and PE in patients with SCD.

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