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Journal of Global Vaccines R&D

Aabstract


Research Article

Presence of the Proteolytic Ferments of Health Cell in Vaccines

Valentina Divocha

Correspondence Address :

Valentina Divocha
Ukrainian Research Institute of Transport Medicine
Odessa, Ukraine
Email: divocha09@ukr.net

Received on: November 03, 2017, Accepted on: November 13, 2017, Published on: November 20, 2017

Citation: Valentina Divocha (2017). Presence of the Proteolytic Ferments of Health Cell in Vaccines

Copyright: 2017 Valentina Divocha. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

  • Abstract

Abstract
The paper is devoted to study presence of components of host cell and its inhibitor in vaccines and blood preparations and to determine the presence trypsin-like proteinase and its inhibitor in vaccines and blood preparations. It is found that influenza virus vaccines (influvac, vaxigrip, fluarix), herpetic and tularemic vaccines contained inhibitor of trypsinlike proteinase in considerable quantity. Commercial preparations of human donor blood (immunoglobulin, interferon, fraxiparine and solcoseryl) contained both trypsin-like proteinase and its inhibitor. The immunoglobulin contained inhibitor 4,0 times more than interferon. Hence, the modern vaccines used for treatment are insufficiently purified and they should be used for treatment taking into account interaction of a flu virus with cellular components (enzymes and inhibitors).

Keywords: Proteolytic ferments, Trypsin-like proteinase, Inhibitor, Vaccines, Immunobiological blood preparations