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Ophthalmology Journals | Eye Journals | Vision Research | High Impact Articles | Scient Open Access
Journal of Ophthalmology & Visual Neuroscience


Research Article

Prevalence of Optic Disc Cupping in Non-Glaucomatous Healthy Saudi Females

Amira Elagamy, Munera Alyahya, Mohamed Berika

Correspondence Address :

Amira Elagamy
Assistant Professor of Ophthalmology
Department of Optometry and Vision Sciences
College of Applied Medical Sciences
King Saud University
Saudi Arabia and Mansoura Ophthalmic Center
Faculty of Medicine, Mansoura University

Received on: March 12, 2018, Accepted on: March 21, 2018, Published on: March 27, 2018

Citation: Amira Elagamy, Munera Alyahya, Mohamed Berika (2018). Prevalence of Optic Disc Cupping in Non-Glaucomatous Healthy Saudi Females

Copyright: 2018 Amira Elagamy. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

  • Abstract

Purpose: This study was conducted to assess optic disc size and cupping in nonglaucomatous healthy Saudi females using Topcon Three-Dimensional (3D) Optical Coherence Tomography (OCT) 2000 - Spectral Domain (SD-OCT), to estimate norms of these values for clinical practice application. Also, the average of the vertical integrated rim area of optic disc in these subjects was determined. Furthermore, correlation of retinal nerve fiber layer (RNFL) thickness and optic disc area in all eyes was evaluated.
Design: This study was a prospective, non-randomized, cross-sectional, observational, and quantitative study.
Methods: The study included 112 eyes of 112 non glaucomatous healthy Saudi females from College of Applied Medical Sciences (CAMS) of King Saud University (KSU). The age range was 18-49 years (mean: 22.50 +/- 5.535 years). Stereoscopic disc photographs were reconstructed using Topcon 3D OCT-2000 for all subjects. Optic disc area, cup/disc ratio, and RNFL thickness were measured. Pearson correlation analysis test was used to assess the correlation between C/D ratio and age, IOP, refractive error. Also, it was used to evaluate the correlation between age and superior RNFL, inferior RNFL thickness respectively. In addition, it was used to assess the relationship between disc area and average RNFL thickness. Level of significance was considered as P < 0.05.
Results: In this study, 100 eyes of 100 subjects enrolled in the analysis of this study.
The range of refractive error was from -4.00 to +4.00 D (-0.8000 +/- 1.28708 D). The range of IOP was from 11.00 to 21.00 mmHg (18.00 +/- 2.503 mm Hg). In this study, the range of the C/D ratio was 0.20 - 0.60 mm2 (0.2976 +/- 0.16500 mm2). Small C/D ratio <0.3 showed the highest percent of all cases (51.0%) while large C/D ratios > 0.6 showed the lowest percent (10.0%). C/D ratio between 0.3-0.6 demonstrated (39.00%). In the current study, the range of disc area was 1.34-5.29 mm2 (2.2196 +/- 0.48084 mm2). Mean total RNFL thickness was 111.39 +/- 11.677μm. There was a statistically significant positive correlation between the disc area and the average RNFL thickness (P = 0.001 & r = 0.322).
Conclusion: This study is the first one to assess the prevalence of non-glaucomatous cupping in healthy Saudi females using Topcon 3D OCT-2000. Further studies are recommended to investigate non glaucomatous cupping in normal Saudi males and in different age groups.

Keywords: Optical Coherence Tomography, Optic disc, Optic cup, Retinal nerve fiber layer thickness