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Journal of Pregnancy and Newborncare

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Research Article

Association between Higher Intake of Fishes and Vegetables during Pregnancy and Full-Term Low Birth Weight Mediated By Placental Weight

Chanmin Wang, Peng Ding, Yan-Hui He, Chuanbo Xie, Zhongzheng Niu, Fu-Ying Tian, Shi-Xin Yuan, De-Qin Jia and Wei-Qing Chen

Correspondence Address :

Wei-Qing Chen
Department of Medical Statistics and Epidemiology
Guangzhou Key Laboratory of Environmental Pollution and Health Assessment
Guangdong Provincial Key Laboratory of Food
Nutrition and Health, School of Public Health, Sun Yat-sen University
74 Zhongshan 2nd Road, Guangzhou, 510080, China
Department of Information Management, Xinhua College, Sun Yat-sen University, Guangzhou, Guangdong
China

Received on: December 12, 2019, Accepted on: December 24, 2019, Published on: December 31, 2019

Citation: Chanmin Wang , Peng Ding , Yan-Hui He , Chuanbo Xie , Zhongzheng Niu , Fu-Ying Tian , Shi-Xin Yuan , De-Qin Jia, Wei-Qing Chen (2019). Association between higher intake of fishes and vegetables during pregnancy and full-term low birth weight mediated by placental weight

Copyright: 2019 Wei-Qing Chen, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

  • Abstract

Abstract
Background: Previous studies have found that maternal dietary intake during pregnancy and placenta play important roles in low birth weight (LBW). However, whether the placenta may play an intermediary role in the association between maternal dietary intake during pregnancy and LBW is still unresolved. This study aimed to investigate this issue.
Methods: 345 pregnant women delivering full-term LBW infants (FT-LBW) and 1791 delivering full-term normal birth weight infants were investigated in this case-control study at Women and Childrens' Hospitals of Shenzhen and Foshan. We collected information about maternal dietary intake during pregnancy, socio-demographic characteristics, and pregnant outcomes. Binary logistic regression models were implemented to estimate the odds ratios (ORs) and 95% confidence intervals (CIs). The intermediary role of placental weight was examined by the bootstrapping procedure of PROCESS macro for SPSS.
Results: After controlling for the potential confounders, maternal higher daily intake of fishes (OR=0.43) and vegetables (OR=0.63) were significantly associated with a lower FT-LBW risk while more intake of milk (OR=1.60) was significantly associated with a higher FT-LBW risk during pregnancy. Furthermore, the mediation results showed that placental weight partially mediated the associations between maternal fishes and vegetables intake during pregnancy and FT-LBW, with the mediation proportion being 10.16% and 14.25% respectively.
Conclusions: Maternal higher intake of fishes and vegetables during pregnancy might reduce the risk of FT-LBW through placenta mediation partially.

Keywords: Dietary intake, Pregnancy, Low birth weight, Placental weight, Mediation