Research Article
Outcomes of Early Liver Retransplantation
Maria Jose Cuevas Lopez
Correspondence Address :
Resident of General Surgery
Hospital Universitario Virgen del Rocio
Spain
DOI: https://doi.org/10.35862/2688-7479/36/27
Received on: February 20, 2019, Accepted on: March 02, 2020, Published on: March 09, 2020
Citation: Citation: Cuevas MJ, Gomez MA(2020) Outcomes of Early Liver Retransplantation.
Copyright: 2020 Gomez MA, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits
unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
Abstract
Introduction: Early liver retransplantation can be defined as the one that takes place within 30 days after primary transplantation, and, traditionally, it has been associated with poor outcomes in terms of morbidity and survival.
The present study aims to identify the factors that adversely affect survival outcomes in these patients.
Methods: A retrospective analysis of the early liver retransplantations performed in a Spanish tertiary care center between 2007 and 2017 was conducted. The variables analyzed were demographics, causes of first transplantation and retransplantation, and mortality resulting from the latter.
Results: 30 early retransplantations were performed during this period, 19 men and 11 women, of a mean age of 52.2 years. The main precipitants of retransplantation were hepatic artery thrombosis (60%) and primary graft failure (13.3%). Perioperative death occurred in 5 recipients (16.7%), most commonly caused by cardiorespiratory arrest (40%). There were not differences between the patients that died and those who lived in terms of MELD score, average age donor or HCV presence. The 1-, 2- and 5-year survival rates were 83.3%, 76.7% and 59.9%, respectively.
Conclusion: in our study we were not able to discern the risk factors that contributed to perioperative death in recipients of early retransplantations. Nevertheless, survival rates among these patients were favorable, almost reaching those reported in global series of liver transplantation.
Keywords: Liver retransplantation, Early liver retransplantation